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. 2022 May 9;29:29. doi: 10.1186/s12929-022-00812-3

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — KDM4A, KDM4B, and KDM4C are overexpressed in PCa. A Expression of KDM4A, KDM4B, and KDM4C in an immortalized prostatic epithelial cell line (RWPE1) and PCa cell lines (LNCaP, C4-2, C4-2B, VCaP, and CWR22Rv1) using Western blotting analysis. Actin served as an internal control. B Expression of KDM4A, KDM4B, and KDM4C in PCa (TCGA) and normal (GTEx) specimens based on the UCSC Xena tool (https://xenabrowser.net). C Analysis of expression of KDM4A, KDM4B, and KDM4C in primary and metastatic PCa tissues based on the Grasso prostate dataset in Oncomine database (https://www.oncomine.org/resource/login.html). Statistical significance was determined using Student's t-test