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Histopathological findings in the rabbit cornea at 24 h after administration
| Findings | Compounds | |||
|---|---|---|---|---|
| Saline | 1% EtBr | 3% MMS | 1% 4-NQO | |
| No. of corneas examined | 1 | 1 | 1 | 1 |
| Degeneration/necrosis, corneal epithelium | – | – | – | ++ |
| Infiltrate, inflammatory cell, corneal limbus | – | – | ± | ± |
| Infiltrate, inflammatory cell, corneal stroma | – | – | – | ± |
−: No abnormal findings, ±: minimal, ++: moderate
EtBr ethidium bromide, MMS methyl methanesulfonate, 4-NQO 4-nitroquinoline 1-oxide
