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Fig. 5. (A) CLSM images of K299 cells after incubation with free DOX, DOX@RE, DOX@RE-4Apt, and DOX@RE-16Apt for 2 h. (B) Flow cytometry histograms of intracellular DOX uptake after incubation with free DOX, DOX@RE, DOX@RE-4Apt and DOX@RE-16Apt for 2 h.