TABLE 4.

Effect of Weight Change on Incidence of Health Problems in the Peri-Pandemic Cohort

	Male		Female
	Odds Ratio∗	95% CI	Odds Ratio∗	95% CI
Hypertension	(N = 17,801)		(N= 15,183)
+ 10 < kg	2.52	1.71–3.70	2.80	1.54–5.09
+6 <∼+10	1.63	1.30–2.05	0.99	0.62–1.60
+2 <∼+6	1.36	1.19–1.55	1.20	0.95–1.51
–2 <∼<+2	1.00	Reference	1.00	Reference
–6∼<–2	0.73	0.61–0.88	0.84	0.62–1.13
–10∼<–6	0.74	0.51–1.06	0.66	0.34–1.27
<–10	0.28	0.12–0.63	0.87	0.37–2.02
p for trend	<0.001		0.001
Hypercholesterolemia	(N= 14,608)		(N= 12,680)
+ 10 < kg	2.76	1.99–3.84	3.15	2.12–4.68
+6<∼+10	2.05	1.69–2.47	1.52	1.15–2.00
+2<∼+6	1.43	1.27–1.62	1.40	1.19–1.64
–2<∼<+2	1.00	Reference	1.00	Reference
–6∼<–2	0.75	0.63–0.89	0.77	0.62–0.96
–10∼<–6	0.41	0.26–0.64	0.98	0.66–1.47
<–10	0.60	0.33–1.10	1.17	0.64–2.16
p for trend	<0.001		<0.001
Hyperglycemia	(N= 17,517)		(N= 14,966)
+ 10< kg	3.02	1.99–4.60	1.83	1.04–3.21
+6<∼+10	1.87	1.45–2.40	1.10	0.76–1.60
+2<∼+6	1.54	1.32–1.80	1.03	0.84–1.27
–2<∼<+2	1.00	Reference	1.00	Reference
–6∼<–2	0.80	0.64–1.00	0.67	0.51–0.89
–10∼<–6	0.59	0.35–0.98	0.54	0.29–0.99
<–10	0.33	0.12–0.90	0.35	0.11–1.11
p for trend	<0.001		<0.001
Liver damage	(N= 17,334)		(N= 15,545)
+ 10< kg	5.16	3.79–7.04	3.54	1.90–6.60
+6<∼+10	3.81	3.18–4.56	2.37	1.57–3.59
+2<∼+6	2.21	1.95–2.51	1.76	1.35–2.30
–2<∼<+2	1.00	Reference	1.00	Reference
–6∼<–2	0.56	0.45–0.70	0.72	0.48–1.09
–10∼<–6	0.18	0.09–0.37	0.88	0.42–1.82
<–10	0.13	0.04–0.41	0.71	0.22–2.26
p for trend	<0.001		<0.001

^∗Adjusted for age and BMI at baseline.