Table 2.

Timeline of patient enrolment/allocation, interventions and assessments

Study periods	Screening	Randomisation	Discharge from ER	Discharge from the acute setting	Day 30	Day 90	Reference diagnosis
Visit	1	2	3	4	5	6	7
Time (hour, day)	hr0	hr2*	hr6*	dx	d30	d90
Demographics	x
Medical history	x
Inclusion/exclusion criteria	x
Physical examination	x
Vital signs	x
Laboratory tests	x			x
CXR, LDCT, LUS		x
Main diagnosis before ER discharge			x				x
Other diagnosis outcomes			x	x			x
Number of antibiotic free days					x
Clinical, safety and cost outcomes				x	x
Readmission and mortality					x	x
QoL questionnaire				x	x	x
Panel of experts							x

*Approximately.

CXR, chest x-ray; d, day; ER, emergency room; hr, hour; LDCT, low-dose CT; LUS, lung ultrasonography; QoL, quality of life.