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. 2022 Apr 25;9:881139. doi: 10.3389/fnut.2022.881139

TABLE 4.

Subgroup analysis of depression for the highest vs. lowest category of dietary beta-carotene intake.

Stratification Number of studies Pooled RR 95% CI P-value Heterogeneity
All studies 8 0.63 0.55, 0.72 P < 0.001 P = 0.31; I2 = 15%
Geographical region
Asia 6 0.64 0.54, 0.76 P < 0.001 P = 0.22; I2 = 27%
Non-Asia 2 0.62 0.50, 0.76 P < 0.001 P = 0.28; I2 = 16%
Exposure assessment
FFQ 6 0.64 0.54, 0.76 P < 0.001 P = 0.22; I2 = 27%
Recall method 2 0.62 0.50, 0.76 P < 0.001 P = 0.28; I2 = 16%
Sex
Male 1 0.36 0.13, 1.00 / /
Female 6 0.65 0.54, 0.78 P < 0.001 P = 0.23; I2 = 28%
Population
Adolescent 3 0.46 0.33, 0.64 P < 0.001 P = 0.82; I2 = 0%
Middle aged and elderly 4 0.67 0.58, 0.78 P < 0.001 P = 0.42; I2 = 0%
Sample size
< 1,000 4 0.46 0.34, 0.62 P < 0.001 P = 0.95; I2 = 0%
> 1,000 4 0.68 0.59, 0.80 P < 0.001 P = 0.37; I2 = 5%
Adjustment of BMI
Adjusted 6 0.62 0.54, 0.72 P < 0.001 P = 0.22; I2 = 28%
Unadjusted 2 0.68 0.46, 1.02 P = 0.06 P = 0.33; I2 = 0%
Adjustment of energy intake
Adjusted 5 0.61 0.52, 0.71 P < 0.001 P = 0.27; I2 = 22%
Unadjusted 3 0.69 0.54, 0.89 P = 0.003 P = 0.34; I2 = 8%