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. 2022 May 9;12:7581. doi: 10.1038/s41598-022-11553-6

Figure 2.

Figure 2

PM10 exposure induces IL-8 in PMNs. (a) IL-8 mRNA expression and (b) IL-8 release in PMNs exposed to different concentrations of PM10 (0.1, 1, 10 and 50 µg/mL) for 5 h. Negative control (culture medium); positive control (LPS). The dotted line illustrates the 1.5-fold increase over the untreated negative control. All data are represented by the mean ± SEM of 8 healthy donors. * p < 0.05; **p < 0.01; ***p < 0.001, by Kruskal–Wallis analysis with post hoc Dunn's test. In (b), the asterisk represents differences compared with the LPS stimulated cells.