Table 2.
Changes in the liver function tests in the serum of male Sprague-Dawley rats treated with EQ and/or BHT for 45 and 90 days
| ALT(u/L) | AST (U/L) | Total bilrubin (mg/dL) | Albumin (g/dL) | ||
|---|---|---|---|---|---|
| The main effect | |||||
| Duration | 45 days | 111.0 b±9.11 | 128.95±4.50 | 0.94 a ±0.05 | 3.50±0.10 |
| 90 days | 159.0 a±15.5 | 131.6±8.40 | 0.85 b±0.10 | 3.40±0.10 | |
| Sig. | *** | NS | * | NS | |
| Treatments | Control | 69.70 c±1.8 | 89.00 c ±6.00 | 0.69 c±0.02 | 3.59±0.16 |
| VH | 70.0 c ±8.40 | 86.6 c±4.00 | 0.70 c±0.10 | 3.24±0.16 | |
| EQ | 128.0 b±3.30 | 122.8 b±5.00 | 0.80 b±0.10 | 3.69±0.14 | |
| BHT | 180.8 a±32.1 | 160.0 a ±6.00 | 1.02 a±0.04 | 3.57±0.04 | |
| EQ+ BHT | 187.0 a ±3.40 | 143.6 a±2.00 | 1.20 a ±0.10 | 3.54±0.10 | |
| Sig. | *** | *** | *** | NS | |
| The interaction effect | |||||
| 45 days | Control | 68 d ±2.72 | 99.00 d±2.00 | 0.87 d±0.10 | 3.65±0.10 |
| VH | 68.66 d ±1.25 | 96.0 d ±1.50 | 0.91 d±0.10 | 3.22±0.32 | |
| EQ | 129.87 c±0 .68 | 166 .0 c ±0.60 | 1.09 c±0.03 | 4.10±0.02 | |
| BHT | 180.0 b±1.50 | 152.6 b±1.70 | 1.20 b±0.02 | 3.48±0.03 | |
| EQ+ BHT | 182.6 b ±5.70 | 140.6 b±4.00 | 1.26 b±0.02 | 3.40 ±1.00 | |
| 90 days | Control | 74.00 d ±2.70 | 99.0 d±10.00 | 0.86 d ±0.10 | 3.54±0.28 |
| VH | 72.0 d±2.80 | 97.0 d±2.00 | 0.90 d±0.02 | 3.27±0.10 | |
| EQ | 137.0 c±1.5 | 169.0 c±1.00 | 1.07 c±0.030 | 3.33±0.05 | |
| BHT | 195 a±1.80 | 185.0 a±2.00 | 1.40 a±0.10 | 3.65±0.02 | |
| EQ+BHT | 191.0 a±3.00 | 176.6 a±1.00 | 1.44 a±0.03 | 3.66±0.17 | |
| Sig. | *** | *** | *** | NS | |
Data are expressed as mean±SD. Means within the same column carrying different superscripts are significant differences (P<0.05) (n=5/group). NS=not significant,*=P<0.05, ***=P<0.001.