Table 4.

Change in rates of liver transplant indication over time by ethnicity and gender

Etiology	White Male 2016 v 2004		White Male 2016 v 2015		White Female 2016 v 2004		White Female 2016 v 2015
	Change	p-value	Change	p-value	Change	p-value	Change	p-value
HCV	−60%	<0.0001	−19%	0.0325	−51%	0.0023	−18%	0.0754
ALD	40%	<0.0001	23%	0.0031	59%	<0.0001	11%	0.4761
NASH	115%	<0.0001	30%	0.0011	75%	<0.0001	15%	0.2499
HCC & HCV	76%	<0.0001	−30%	<0.0001	147%	<0.0001	−34%	0.0032
HCV & ALD	−50%	<0.0001	−13%	0.3364	−33%	0.7150	−11%	0.5297
HCC& NASH	877%	<0.0001	32%	0.0594	1042%	0.0001	−10%	0.5413
HCC & ALD	121%	<0.0001	−12%	0.4873	n/a	0.8867	−38%	0.2245
Etiology	Hispanic Male 2016 v 2004		Hispanic Male 2016 v 2015		Hispanic Female 2016 v 2004		Hispanic Female 2016 v 2015
	Change	p-value	Change	p-value	Change	p-value	Change	p-value
HCV	−48%	0.1939	−17%	0.6369	−69%	0.0003	−26%	0.9582
ALD	26%	0.0099	4%	0.4803	62%	0.1808	1%	0.2915
NASH	240%	<0.0001	37%	0.0791	122%	0.0041	19%	0.3648
HCC & HCV	109%	0.0007	−9%	0.9536	560%	0.0060	−18%	0.8301
HCV & ALD	−50%	0.1930	2%	0.6563	−59%	0.1017	33%	0.2008
HCC & NASH	720%	0.0175	−7%	0.9749	749%	0.0264	10%	0.5864
HCC & ALD	235%	0.0045	38%	0.1680	n/a	0.9834	−59%	0.4801
Etiology	AA Male 2016 v 2004		AA Male 2016 v 2015		AA Female 2016 v 2004		AA Female 2016 v 2015
	Change	p-value	Change	p-value	Change	p-value	Change	p-value
HCV	−36%	0.1625	14%	0.6539	−43%	0.0449	−26%	0.0858
ALD	88%	0.0594	53%	0.1986	−20%	0.5601	−13%	0.4280
NASH	−3%	0.8627	−9%	0.7752	157%	0.1622	34%	0.7373
HCC & HCV	171%	0.0004	−23%	0.1325	50%	0.3749	−28%	0.0823
HCV & ALD	−19%	0.8326	0%	0.9185	8%	0.9484	19%	0.9778
HCC & NASH	n/a	0.9850	0%	0.9803	n/a	0.9906	−38%	0.4857
HCC & ALD	−19%	0.9106	−16%	0.7258	n/a	0.9999	−100%	0.9854
Etiology	Asian Male 2016 v 2004		Asian Male 2016 v 2015		Asian Female 2016 v 2004		Asian Female 2016 v 2015
	Change	p-value	Change	p-value	Change	p-value	Change	p-value
HCV	−50%	0.1456	−12%	0.7087	−55%	0.3071	−47%	0.2713
ALD	223%	0.0198	−5%	0.8352	n/a	0.9924	321%	0.1741
NASH	597%	0.0482	76%	0.2544	n/a	0.9850	96%	0.1303
HCC & HCV	9%	0.5996	2%	0.9961	31%	0.4726	47%	0.4249
HCV & ALD	0%	0.9228	−12%	0.8857	n/a	0.9965	n/a	0.9952
HCC & NASH	n/a	0.9762	−67%	0.1025	n/a	0.9918	−30%	0.7946
HCC & ALD	−50%	0.4894	32%	0.7776	n/a	0.9999	n/a	0.9999

Percent change computed from observed counts over time and p-values computed from multinomial regression analysis within each ethnicity and gender; n/a indicates percent change not computed due to zero observations in divisor

AA African Americans, HCV Hepatitis C virus, ALD Alcoholic liver disease, NASH Non-alcoholic steatohepatitis, HCC Hepatocellular carcinoma