Table 1.
Autoantibody characteristics of AIH patients, PBC patients and OS patients.
| AIH | PBC | OS | P1 | P2 | |
|---|---|---|---|---|---|
| Sex (M/F) | 10/49 | 3/23 | 1/21 | 0.746 | 0.273 |
| Age (years), median (IQR) | 54 (16.5) | 52.5 (12.25) | 55 (22.25) | 0.731 | 0.421 |
| anti-SMA, % | 13/54 (24.1%) | 0/19 (0%) | 0/16 (0%) | 0.063 | 0.114 |
| ANA, % | 33/54 (61.1%) | 14/19 (73.7%) | 10/16 (62.5%) | 0.139 | 1.000 |
| anti-Ro52, % | 13/48 (27.1%) | 8/23 (34.8%) | 11/16 (68.8%) | 0.618 | <0.05 |
| anti-SLA, % | 1/48 (2.1%) | 0/23 (0%) | 1/16 (6.3%) | 1.000 | 0.440 |
| anti-PML, % | 2/48 (4.2%) | 1/23 (4.3%) | 5/16 (31.3%) | 1.000 | <0.05 |
| anti-gp210, % | 3/48 (6.3%) | 10/23 (43.5%) | 8/16 (50%) | <0.05 | <0.05 |
| anti-sp100, % | 5/48 (8.3%) | 3/23 (13.0%) | 3/16 (18.8%) | 0.585 | 0.374 |
| AMA-M2-3E, % | 5/48 (8.3%) | 17/23 (73.9%) | 9/16 (56.3%) | <0.05 | <0.05 |
| AMA-M2, % | 4/48 (8.3%) | 15/23 (65.2%) | 6/16 (37.5%) | <0.05 | <0.05 |
| anti-LC-1, % | 2/48 (4.2%) | 0/23 (0%) | 2/16 (12.5%) | 1.000 | 0.258 |
| anti-LKM-1, % | 0/48 (0%) | 0/23 (0%) | 0/16 (0%) | / | / |
AIH, autoimmune hepatitis; PBC, primary biliary cholangitis; OS, overlap syndrome.
P1, the difference between AIH and PBC group; P2, the difference between AIH and OS group.