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Effects of TSF treatment on serum metabolites and gut microbiota. (A) TSF treatment significantly improved levels of 16 metabolites in DKD rats as determined using Wilcoxon rank-sum test (*p < 0.05, **p < 0.01). (B) Effect of TSF treatment on gut microbiota at the OTU level. (C) Relative abundance of genera changes in the TSF group compared with the DKD group.
