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. 2022 May 9;12:7596. doi: 10.1038/s41598-022-11680-0

Table 5.

Active PPI use: outcomes based on PPI dosage (n = 286)*.

Low
(n = 70)
Standard
(n = 190)
High
(n = 26)
p-value**

Hospital admission within two weeks of COVID testing

(n,%)

68 (97.1%) 182 (95.8%) 25 (96.2%) .88

ICU admission

(n,%)

16 (22.9%) 52 (27.4%) 9 (34.6%) .50

Hospital length of stay, days

(median, range)

1 (1–33) 3 (1–32) 3.5 (1–45) .07

Oxygen use

(n,%)

Mechanical ventilation: 7 (10%)

BPAP: 1 (1.4%)

Supplemental: 47 (67.1%)

None: 15 (21.4%)

Mechanical ventilation: 28 (14.7%)

BPAP: 1 (0.5%)

Supplemental: 106 (55.8%)

None: 55 (28.9%)

Mechanical ventilation: 6 (23.1%)

BPAP: 0

Supplemental: 14 (53.8%)

None: 6 (23.1%)

.47

30-day mortality

(n,%)

10 (14.3%) 37 (19.5%) 7 (26.9%) .35

*PPI Proton pump inhibitor.

**Based on separate chi square or Kruskal Wallis tests, as appropriate.