TABLE 2.
p62-positive structures in Alzheimer’s disease (AD).
PART | Age | Sex | Neocortical |
Thalamus |
Basal ganglia |
Hippocampus |
Brainstem |
Ce | SC | ||||||||||||||
GPP | T | F | GC | LPI | P | O | H | TS | CP | PPI | AE | HA | HM | HL | SN | CIP | LCP | MO | |||||
III | 69 | F | – | – | – | – | – | – | – | – | – | – | – | + | + | + | + | + | – | + | + | – | – |
73 | M | – | + | + | ++ | – | – | – | + | + | + | + | + | + | + | + | + | ++ | + | ++ | – | ||
79 | F | – | + | – | – | – | – | – | – | + | – | + | + | + | + | + | – | + | + | – | + | – | |
93 | F | + | + | – | + | – | – | – | – | – | – | – | + | ++ | + | – | + | – | – | – | – | – | |
IV | 78 | M | – | + | – | – | – | – | – | + | – | – | – | + | + | + | – | – | + | + | + | – | – |
81 | F | – | + | + | ++ | – | – | – | + | – | – | + | ++ | +++ | + | ++ | – | + | + | + | – | – | |
83 | M | – | + | – | – | – | – | – | + | – | – | – | +++ | + | + | + | – | + | + | + | – | – | |
V | 98 | F | – | – | + | + | ++ | ++ | + | + | + | – | – | +++ | +++ | + | ++ | – | + | + | + | – | – |
VI | 79 | M | + | + | +++ | +++ | ++ | +++ | +++ | ++ | ++ | + | +++ | ++ | +++ | + | ++ | + | + | – | + | – | – |
85 | M | – | + | + | ++ | ++ | + | +++ | +++ | +++ | +++ | + | +++ | + | + | + | + | + | – | – | |||
87 | F | + | + | +++ | +++ | +++ | + | + | ++ | + | +++ | +++ | +++ | + | +++ | + | ++ | + | + | – | – |
GPP, gyrus pre/postcentralis; T, temporal pole; F, frontal lobe; GC, gyrus cinguli; LPI, lobular parietal inferior; P, parietal; O, occipital lobe; H, hypothalamus; TS, thalamus/subthalamus; CP, caudatum/Putamen; PPI, putamen/pallidum/insular; AE, amygdala/entorhinal cort; HA, hippocampus anterior; HM, hippocampus middle; HP, hippocampus post; SN, substantia nigra; CIP, colliculus inferior/pons; LCP, Loc. coeruleus/pons; MO, medulla oblongata; Ce, cerebellum; SC, spinal cord cervical.