IC₅₀-values of glycoclusters (given in mM based on GalNAc) and the cognate monosaccharide in lectin histochemical assays with biotinylated lectins applied to sections of fixed murine jejunum.

Compound/cell type	DBA	SBA	HPA	MGL
				CRD	CRD + stalk
1
Surface enterocytes	n.i.a	10.0 (0.05)b	>10.0 (<0.5)	>20.0 (<1.25)	>20.0 (<1.25)
Crypt-associated cells	n.i.a	20.0 (0.1)	>20.0 (<0.25)	>20.0 (<2.5)	>20.0 (<2.5)
2
Surface enterocytes	1.0 (25)	0.02/0.01 (50/100)	5.0 (1.0)	1.0 (25)	1.0 (25)
Crypt-associated cells	2.0 (25)	0.01 (200)	5.0 (1.0)	1.0 (50)	2.0 (25)
3
Surface enterocytes	2.0 (12.5)	0.005/0.002 (200/500)	0.1/0.05 (50/100)	0.05 (500)	0.1 (250)
Crypt-associated cells	5.0 (10)	0.005/0.002 (200/500)	0.5/0.2 (10/25)	0.05 (1000)	0.1 (500)
4
Surface enterocytes	1.0 (25)	0.005 (200)	1.0 (5.0)	0.05/0.02 (500/1250)	0.1/0.05 (250/500)
Crypt-associated cells	5.0 (5)	0.01 (200)	5.0 (1.0)	0.05/0.02 (1000/2500)	0.1/0.05 (500/1000)
5
Surface enterocytes	2.0 (12.5)	0.001/0.0005 (1000/2000)	0.05/0.02 (100/250)	0.01/0.005 (2500/5000)	0.005 (5000)
Crypt-associated cells	5.0 (10)	0.001 (2000)	0.02 (250)	0.01/0.005 (5000/10 000)	0.005/0.002 (10 000/25 000)
6
Surface enterocytes	20 (1.4)	0.1 (10)	0.1 (50)	0.2 (125)	0.1 (250)
Crypt-associated cells	>20 (<2.5)	0.2 (10)	0.2 (25)	0.2 (250)	0.2/0.1 (250/500)
7
Surface enterocytes	20 (1.25)	0.02 (50)	0.5 (10.0)	5.0 (5)	10.0 (2.5)
Crypt-associated cells	>20 (<2.5)	0.05 (40)	2.0 (2.5)	1.0 (50)	2.0 (25)
d-GalNAc
Surface enterocytes	25.0	1.0	5.0	25.0	25.0
Crypt-associated cells	50.0	2.0	5.0	50.0	50.0

^an.i.: not inhibitory; tested up to 20 mM.

^bNumbers in parentheses denote relative inhibitory potency using activitiy of free GalNAc as standard set to 1.