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. 2022 May 9;12(22):13896–13916. doi: 10.1039/d2ra00966h

Levels, factors, and responses of the proposed experimental design.

Factors Responses
Experiment no. Temperature % of organic solvent pH RSDFX & DFP RSDFP & IS TFDFX TFDFP Run time
1 25 60 5 5.05 2.99 1.23 1.32 10.00
2 25 70 3 2.21 2.25 1.11 1.02 6.00
3 35 70 3 1.01 1.99 1.24 1.20 6.41
4 25 70 7 2.14 3.05 1.44 1.33 6.10
5 25 60 7 3.55 3.03 1.32 1.29 10.20
6 25 65 3 3.25 2.88 1.23 1.16 7.22
7 30 65 7 1.55 2.53 1.42 1.40 7.51
8 30 70 5 1.65 1.95 1.28 1.32 6.00
9 35 70 7 0.89 1.03 1.34 1.29 5.45
10 25 70 7 2.08 2.98 1.40 1.35 6.11
11 30 65 5 1.70 2.63 1.33 1.30 7.06
12 35 65 5 2.14 2.49 1.34 1.48 6.38
13 25 60 3 5.14 3.10 1.15 1.25 10.00
14 30 60 3 4.54 2.88 1.31 1.51 9.44
15 35 60 3 2.87 2.99 1.22 1.08 8.89
16 35 60 7 2.10 3.71 1.45 1.32 8.68