Pharmacokinetic parameters of deferasirox and deferiprone in rat plasma after I. V administration of 185 mg kg⁻¹ of DFX and 465 mg kg⁻¹ of DFP.

Parameters	DFX		DFP
	Single administration gp	Combined administration gp	Single administration gp	Combined administration gp
t 1/2 (h)	7.92 ± 1.14	7.15 ± 0.60	9.29 ± 1.13	9.26 ± 1.14
C max (μg mL−1)	38.05 ± 3.08	41.28 ± 3.21	35.25 ± 3.63	36.66 ± 4.11
T max (h)	1.50 ± 0.51	1.50 ± 0.53	1.00 ± 0.21	1.00 ± 0.22
Elimination rate constant (K)	0.088 ± 0.05	0.097 ± 0.04	0.075 ± 0.02	0.075 ± 0.03
Volume of distribution (Vd) (L)	9.83 ± 1.91	9.38 ± 1.46	28.27 ± 2.86	27.30 ± 2.70
Clearance (cl) (L h−1)	0.89 ± 0.09	0.91 ± 0.23	2.11 ± 0.23	2.04 ± 0.38
AUC 0→t (μg mL−1 h−1)	12.23 ± 1.89	12.96 ± 1.67	17.66 ± 2.54	16.44 ± 2.98
AUC 0→∞ (μg mL h−1)	275.39 ± 7.70	278.26 ± 3.66	256.86 ± 6.34	304.52 ± 5.71