Comparison of the greenness profile assessment of the proposed HPLC method and the reported ones.
| Green assessment tool | Developed HPLC method | Reported method for DFX | Reported method for DFP |
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| National environmental methods index (NEMI) |
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| Modified NEMI |
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| Analytical method volume intensity (AMVI) | 51.0 | 145.0 | 89.2 |
| Eco-scale | 90.0 | 90.0 | 86.0 |
| Analytical method greenness score (AMGS) | 163.89 | 641.37 | 257.44 |
| Environmental assessment tool (HPLC-EAT) | 50.30 | 88.69 | 72.53 |
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| Green analytical procedure index (GAPI) |
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| Analytical GREEnness (AGREE) |
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