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. Author manuscript; available in PMC: 2022 May 9.
Published in final edited form as: Neurobiol Dis. 2018 Jun 23;126:47–61. doi: 10.1016/j.nbd.2018.05.011

Figure 4. CK2 inhibition prevents OGD-induced axon injury and oligodendrocyte death.

Figure 4.

OGD (1 h) caused widespread loss of SMI-31 (+) axons (green) and adenomatous polyposis coli (APC (+), oligodendrocytes, magenta), while CX-4945 (5 μM) prevented axonal injury and oligodendrocyte loss. Glial nuclei were labeled with Sytox (blue, arrows). Note that the merged images in the right panels are enlarged areas indicated by the squares with dashed lines in the middle panels. Scale bar = 20 μm.