Skip to main content
. Author manuscript; available in PMC: 2022 May 9.
Published in final edited form as: Neurobiol Dis. 2018 Jun 23;126:47–61. doi: 10.1016/j.nbd.2018.05.011

Figure 8. ARQ-092, a novel pan-AKT inhibitor, promotes axonal recovery when applied pre- and post-OGD.

Figure 8.

ARQ-092, which is an inhibitor of activated AKT, promoted axon function recovery when applied as a pre-treatment and as a post-treatment. A) Pre-treatment with ARQ-092 (500 nM, dark blue) applied before OGD promoted consistent and sustained CAP area recovery. B) ARQ-092 improved CAP area recovery at 250 nM and 500 nM when compared to control CAP area recovery. C) ARQ-092 (500 nM, brown) applied after OGD promoted consistent and sustained CAP area recovery. D) ARQ-092 improved CAP area recovery at 250 and 500 nM compared to control CAP area recovery. * p <0.05 and ** p < 0.01, one-way ANOVA with Newman-Keuls post hoc test.