Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Apr 13;60(6):64. doi: 10.3892/ijo.2022.5354

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright: © Chang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

PMC Copyright notice

Representative immunohistochemical staining images for the expression of p53 and CSE1L proteins in the colon tissues. Colon tissues were sectioned from the following different groups: Control group, consisting of mice that did not receive any chemical treatment or B. pullicaecorum admin-istration; DMH/DSS group, consisting of mice that received DMH through intraperitoneal injection and DSS in their drinking water but did not receive B. pullicaecorum; and DMH/DSS/B. pullicaecorum group, consisting of mice that received DMH/DSS and B. pullicaecorum. Colon tumors exhibited weak nuclear staining of p53 and markedly increased expression of CSE1L. Insets show the magnified views of the boxed areas. Red arrows indicate the intramucosal adenocarcinoma in DMH/DSS group (middle panel) and the low-grade adenoma in DMH/DSS/B. pullicaecorum group (right panel). Scale bar, 50 µm for inset. CSE1L, chromosome segregation 1-like protein; DMH, 1,2-dimethylhydrazine; DSS, dextran sulphate sodium; B. pullicaecorum, Butyricicoccus pullicaecorum.