Table 4 –
Multivariable Cox regression analysis predicting clinical recurrence after SLND in 654 patients treated for nodal recurrence of prostate cancer
| Predictor | HR | 95% CI | p value |
|---|---|---|---|
| Gleason grade group | |||
| ≤4 | 1.00 | Ref. | – |
| 5 | 2.04 | 1.66–2.50 | <0.0001 |
| Time from RP to PSA rising, per 6 mo | 0.98 | 0.96–0.99 | 0.025 |
| HT administration at the time of PET/CT scan | |||
| No | 1.00 | Ref. | – |
| Yes | 1.47 | 1.19–1.82 | 0.0005 |
| Retroperitoneum involvement at PET/CT scan | |||
| No | 1.00 | Ref. | – |
| Yes | 1.24 | 1.01–1.52 | 0.038 |
| Positive spots at PET/CT scan | |||
| ≤2 | 1.00 | Ref. | – |
| ≥3 | 1.26 | 1.05–1.61 | 0.019 |
| PSA at SLND, ng/ml | 1.05 | 1.04–1.07 | <0.0001 |
CI = confidence interval; HR = hazard ratio; HT = hormonal therapy; PET/CT = positron emission tomography/computed tomography; PSA = prostate-specific antigen; Ref. = reference; RP = radical prostatectomy; SLND = salvage lymph node dissection.