Ub |
Ubiquitin |
E1 |
Ub-activating enzyme |
E2 |
Ub-conjugating enzyme |
E3 |
Ub ligase |
LUBAC |
The linear ubiquitin chain assembly complex |
SHARPIN |
SHANK-associated RH domain-interacting protein |
HOIP |
Ring finger protein 31 |
HOIL-1L |
RanBP-type and C3HC4-type zinc finger containing 1 |
cpdm |
chronic proliferative dermatitis mice |
UBL |
ubiquitin-like domain |
NZF |
Npl4-zinc finger domain |
UBA |
ubiquitin-associated domain |
RBR |
RING-between RING |
PUB |
UBX-containing protein |
ZF |
zinc finger |
NZF |
Nlp4-like ZF domains |
LDD |
linear Ub chain determining domain |
NEMO |
Inhibitor of kappaB kinase gamma |
NF-κB |
Nuclear factor kappa B |
LTM |
LUBAC-tethering motif |
TD |
Tethering domain |
ATM |
ataxia telangiectasia mutated |
IKKα |
Nuclear factor of kappa light polypeptide gene enhancer, alpha |
IKKβ |
Nuclear factor of kappa light polypeptide gene enhancer,beta |
Eya1 |
Eyes absent 1 protein |
BOR |
Branchio-oto-renal |
TNF |
tumor necrosis factor |
TRADD |
TNFR1-associated death domain protein |
TRAF2 |
TNF receptor-associated factor 2 |
cIAPs |
cellular inhibitor of apoptosis |
RIPK1 |
receptor interacting protein kinase 1 |
PTEN |
phosphatase and tensin homolog |
PTEN-NRs |
negative regulatory protein of PTEN |
SIPL1 |
class SHANK interacting protein 1 |
PIP3 |
phosphorylation of 3 phosphate |
ERα |
estrogen receptor alpha |
MDM2 |
(mouse double minute 2 homolog |
Rap1 |
Ras-associated protein-1 |
Pvhl |
Von Hippel-Lindau protein |
HIF |
hypoxia-induced factor |
PHD |
prolyl hydroxylase domain-containing protein |
AD |
Alzheimer’s disease |
Aβ |
amyloid-beta |
LOAD |
late-onset Alzheimer’s disease |