Table 2.
Scope of Aryl Iodides[a]
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Conditions: 1a (0.25 mmol, 2.5 equiv), 2 (0.1 mmol, 1.0 equiv), Pd(OAc)2 (10 mol %), TDG1 (30 mol %), L4 (50 mol %), Ag3PO4 (70 mol %), CsOAc (1.0 equiv.), HFIP (0.6 mL), 100 °C, under air, 24‒48 h.
3% di-arylation product on β-tertiary and γ-methylene C‒H bonds was observed