TABLE 1.
Susceptibility testing of American Type Culture Collection strains and clinical isolates of P. aeruginosaa
| Strain | Age (yr) | Location | Susceptibilityb | Muciodc | Assayd | MIC
(μg/ml)
|
|
|---|---|---|---|---|---|---|---|
| P-113 | P-113d | ||||||
| ATCC 19142 | DA | 3.1 | |||||
| ATCC 19143 | DA | 3.1 | |||||
| ATCC 27853 | DA | 6.3 | 3.1 | ||||
| ATCC 43393 | DA | 6.3 | |||||
| ATCC 51674 | DA | 1.6 | |||||
| 332 | Yes | DA | 6.3 | 6.3 | |||
| 8050-2 | Yes | DA | 3.1 | 3.1 | |||
| 5681-1 | Yes | DA | 6.3 | 3.1 | |||
| 2192 | Yes | DA | 6.3 | 3.1 | |||
| 1-76 AM | 51 | Cleveland, Ohio | R | DA | 3.1 | 1.6 | |
| 1-77 AM | 27 | Dallas, Tex. | R | DA | 1.6 | 1.6 | |
| 1-78 AM | 20 | Birmingham, Al. | R | AB | 1.6 | ||
| 1-82 AM | 14 | St. Louis, Mo. | R | DA | 3.1 | ||
| 2-17 AM | 10 | Los Angeles, Calif. | RR | DA | 3.1 | 1.6 | |
| 2-24 AM | 15 | Atlanta, Ga. | R | AB | 1.6 | ||
| 2-25 AM | 21 | Durham, N.C. | R | DA | 1.6 | 1.6 | |
| 2-87 AM | 21 | Falls Church, Va. | R | DA | 1.6 | 1.6 | |
| 2-90 AM | 26 | Cincinnati, Ohio | R | DA | 1.6 | 3.1 | |
| 2-98 AL | 33 | Cleveland, Ohio | RR | Yes | DA | >100 | >50 |
| 3-16 AL | 23 | Providence, R.I. | R | AB | 1.6 | ||
| 3-20 AL | 23 | Fort Worth, Tex. | R | DA | 3.1 | 1.6 | |
| 3-36 AM | 26 | Tulsa, Okla. | R | DA | 3.1 | 1.6 | |
| 3-47 AM | 24 | Peoria, Ill. | R | AB | 1.6 | ||
| 3-66 AM | 23 | Oklahoma City, Okla. | R | DA | 3.1 | 3.1 | |
| 4-34 AL | 19 | Chattanooga, Tenn. | R | AB | 3.1 | ||
| 4-36 AL | 22 | Oklahoma City, Okla. | RR | DA | >50 | 25 | |
| 4-68 AL | 17 | Pittsburgh, Pa. | r1 | AB | 3.1 | ||
| 4-97 AL | 17 | San Francisco, Calif. | R | DA | 3.1 | 3.1 | |
| 5-39 AM | 21 | Phoenix, Ariz. | r3 | DA | 6.3 | ||
Strains obtained from the American Type Culture Collection (ATCC) are so designated. The other strains are clinical isolates from CF patients from Lisa Saiman at (Columbia University). Strains 332, 8050-2, 5681-1, and 2192, however, were from Gerald Pier (Harvard University). Geographic data and susceptibility data obtained by standard methods (38) are included.
R, resistant to all antibiotics tested (ceftazidime, amikacin, piperacillin, aztreonam, tobramycin, gentamicin, ticarcillin, and timentin); RR, resistant to high doses of tobramycin and gentamicin; r1, resistant to all antibiotics tested except ticarcillin and timentin; r3, resistant to all antibiotics tested except tobramycin and amikacin.
Yes indicates mucoid colonial morphology.
AB, Alamar Blue method; DA, direct assay, method (see Materials and Methods).