Table 3. Univariate and multivariate Cox regression analyses for outcomes in N− adjuvant patients after matching (n = 78).
| OS | ||||
|---|---|---|---|---|
| Univariate | Multivariate | |||
| Factor | HR (95% CI) | p | HR (95% CI) | p |
| Lymphovascular invasion | ||||
| Absent | 1 | 1 | ||
| Present | 12.597 (1.624–97.728) | 0.015 | 12.597 (1.624–97.728) | 0.015 |
| T | ||||
| T1 | 1 | |||
| T2 | 3.418 (0.440–26.541) | 0.240 | ||
| T3 | 2.197 (0.137–35.309) | 0.579 | ||
| Histological grade | ||||
| G1/G2 | 1 | |||
| G3 | 2.374 (0.774–7.276) | 0.130 | ||
| Molecular subtype | ||||
| Luminal A | 1 | |||
| Luminal B | 1.784 (0.327–9.748) | 0.504 | ||
| HER2 | 1.958 (0.274–13.965) | 0.503 | ||
| Triple-negative | 4.398 (0.846–22.868) | 0.078 | ||
| DMFS | ||||
| Lymphovascular invasion | ||||
| Absent | 1 | 1 | ||
| Present | 7.905 (0.969–64.509) | 0.054 | 7.905 (0.969–64.509) | 0.054 |
| T | ||||
| T1 | 1 | |||
| T2 | Undefined | 0.955 | ||
| T3 | Undefined | 0.955 | ||
| Histological grade | ||||
| G1/G2 | 1 | |||
| G3 | 3.812 (0.948–15.326) | 0.059 | ||
| Molecular subtype | ||||
| Luminal A | 1 | |||
| Luminal B | Undefined | 0.950 | ||
| HER2 | Undefined | 0.949 | ||
| Triple-negative | Undefined | 0.947 | ||
G1 – well differentiated; G2 – moderately differentiated; G3 – poorly differentiated; T – tumour size