Table 4. Univariate and multivariate Cox regression analyses for outcomes in N+ adjuvant patients after matching (n = 66).

OS
	Univariate		Multivariate
Factor	HR (95% CI)	p	HR (95% CI)	p
Lymphovascular invasion
Absent	1
Present	2.139 (0.741–6.174)	0.160
T
T1	1
T2	2.461 (0.836–7.244)	0.102
T3	2.653 (0.332–20.935)	0.359
N
N1	1
N2	2.461 (0.836–7.244)	0.102
N3	2.635 (0.332–20.935)	0.359
Histological grade
G1/G2	1		1
G3	4.721 (1.534–14.523)	0.007	4.721 (1.534–14.523)	0.007
Molecular subtype
Luminal A	1
Luminal B	9.676 (1.236–75.773)	0.031
HER2	4.154 (0.375–46.002)	0.246
Triple-negative	10.333 (1.144–93.360)	0.038
DMFS
Lymphovascular invasion
Absent	1		1
Present	3.299 (1.196–9.102)	0.021	4.862 (1.649–14.335)	0.004
T
T1	1
T2	1.896 (0.553–6.498)	0.309
T3	Undefined	0.981
N
N1	1
N2	1.800 (0.647–5.010)	0.260
N3	1.494 (0.191–11.666)	0.702
Histological grade
G1/G2	1
G3	2.090 (0.670–6.525)	0.204
Molecular subtype
Luminal A	1		1
Luminal B	5.355 (1.169–24.533)	0.031	8.008 (1.675–38.294)	0.009
HER2	4.445 (0.813–24.313)	0.085	3.862 (0.704–21.203)	0.120
Triple-negative	5.770 (1.052–31.648)	0.044	8.572 (1.530–48.028)	0.015

G1 – well differentiated; G2 – moderately differentiated; G3 – poorly differentiated; N – lymph node metastasis