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. 2022 Apr 25;14:831967. doi: 10.3389/fnagi.2022.831967

TABLE 1.

Top 10 genes for classifying the subjects into dementia and no cognitive impairment and for classifying subjects into mild cognitive impairment and dementia.

Dementia vs. no Dementia vs. mild
cognitive impairment
cognitive impairment
Gene symbol z-score Direction* Gene symbol z-score Direction*
PRTN3 7.51 Down PRPF4 7.59 Down
SLC4A11 6.60 Up ADAMTS2 5.82 Up
MEIS3 6.06 Down RPSAP15 5.81 Down
AGPAT1 6.05 Down PRTN3 5.33 Down
GSEC 5.93 Down KIF5A 5.13 Up
PPDPF 5.82 Down TACR2 4.95 Down
ARHGEF34P 5.58 Up BRD1 4.94 Up
TCP10L 5.51 Down OVCH1-AS1 4.78 Down
IL15 5.49 Up ANKRD30B 4.48 Down
NUMBL 4.90 Down NPPA 4.36 Down

*Higher or lower mean expression in dementia.