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. 2022 Apr 25;14:831967. doi: 10.3389/fnagi.2022.831967

TABLE 2.

Top 10 genes for classifying the subjects into fast episodic memory decline and slow episodic memory decline and top 10 genes predictive of episodic memory in the full cohort.

Gene symbol z-score Direction* Gene symbol z-score Cor.*
PRTN3 7.47 Down PRTN3 7.45 +
ADAMTS2 6.22 Up ADAMTS2 6.83
PPM1D 5.92 Up ZCCHC10 6.43 +
ENSG00000216895 5.3 Down TAF1D 6.3 +
LINC02172 5.18 Up CCN4 5.76
SLC6A9 4.95 Up ZNF334 5.59 +
TMEM72-AS1 4.88 Down HMGN2 5.48 +
PPP4R1 4.8 Up PPP4R1 5.47
QDPR 4.57 Up SLC4A11 4.99
ZNF334 4.56 Down ANKRD19P 4.96 +

*Higher or lower mean expression in dementia.

*Pearson correlation between gene and slope of episodic memory decline.