U-exo |
small extracellular vesicles derived from human umbilical cord mesenchymal stem cells |
IFV |
human influenza A/B virus |
HCoV |
human seasonal coronavirus |
IFN-α |
interferon-alpha protein |
ALI |
air-liquid interface |
SARS-CoV-2 |
severe acute respiratory syndrome coronavirus 2 |
MERS-CoV |
middle east respiratory syndrome coronavirus |
SARS-CoV-1 |
severe acute respiratory syndrome coronavirus 1 |
EVs |
extracellular vesicles |
miRNAs |
microRNAs |
MSCs |
mesenchymal stem cells |
HCV |
Hepatitis C virus |
UCMSCs |
umbilical cord-derived mesenchymal stem cells |
HNECs |
primary human nasal epithelial cells |
A549 |
human lung adenocarcinoma cells |
HCT8 |
human colorectal adenocarcinoma cells |
MRC5 |
human lung embryonic fibroblast cells |
NS1 |
non-structural protein 1 |
IFV-PR8delNS1 |
Human influenza virus A/Puerto-Rico/8/34 PR8 lacking NS1 |
MOI |
multiplicity of infection |
TCID50
|
tissue culture infectious dose |
hpi |
hours post-infection |
NTA |
Nanoparticle Tracking Analysis |
TEM |
transmission electron microscopy |
MTT |
3-(4, 5-dimethylthiazolyl-2)-2,5-diphenyltetrazolium bromide |
LDH |
lactate dehydrogenase |
GAPDH |
Glyceraldehyde 3-phosphate dehydrogenase |
DAPI |
4,6-diamidino-2-phenylindole |
TEER |
trans-epithelial electrical resistance |
H&E |
hematoxylin and eosin |
CM |
Conditioned medium |
HBV |
Hepatitis B virus |
sEVs |
small EVs |
RLR |
retinoic acid-inducible gene I-like receptors |
RIG-I |
retinoic acid-inducible gene-I |
MDA5 |
melanoma differentiation associated gene 5 |
MAVS |
mitochondrial antiviral signaling protein |
STING |
stimulator of interferon response c-GAMP interactor 1 |
Mx1 |
MX dynamin like GTPase 1 |
ISG15 |
interferon-stimulated gene 15 |
OAS1 |
2’-5’-oligoadenylate synthetase 1 |
IFITM3 |
interferon induced transmembrane protein 3 |
IFN-β |
interferon-beta |
IFN-λ1 |
interferon-lambda 1 |
ISGs |
interferon-stimulated genes |
JAK/STAT |
Janus kinase/signal transduction and activator of transcription signaling pathways |