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. 2022 May 9;8:61. doi: 10.1038/s41523-022-00423-z

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — ^aAvailable ROR score categories in n = 219 and n = 216 patients in the control (no systemic treatment) and tamoxifen arm, respectively, due to n = 1 missing nodal status for one patient in each treatment arm. ^bDefined accordingly: LumA_SC, low Ki67 (<20%) and high PR (≥20%); LumB_SC, high Ki67 (≥20%) and/or low PR (<20%). Cases with missing re-evaluated PR data were substituted (n = 2 in the control arm) with previously available IHC data for PR. ER oestrogen receptor, HER2 human epidermal growth factor receptor 2, IHC immunohistochemistry, Lum Luminal, PR progesterone receptor, ROR risk of recurrence, SC surrogate classification, TAM tamoxifen.