Fig. 10. TiO2 NPs depolarized the membrane of HepG2 cells. L02 and HepG2 cells were co-cultured with different concentrations of TiO2 NPs in 6-well plates for 48 h and then, a JC-10 detection kit was used to analyze changes in the mitochondrial membrane of the cells. (A) In L02 cells, there was no significant decrease in the ratio of red to green fluorescence. (B) In HepG2 cells, the ratio of red to green fluorescence decreased in a concentration-dependent manner. All data are presented as the mean ± standard error of the mean. *p < 0.05, **p < 0.01.
