TABLE 3.
Parameter | Total | No. of patients in dosage group:
|
|||
---|---|---|---|---|---|
7.5 mg/kg | 10 mg/kg | 12.5 mg/kg | 15 mg/kg | ||
No. of patients | 44 | 8 | 10 | 7 | 19 |
No. of daily infusions | |||||
Mean ± SD | 18.5 ± 18.5 | 23.9 ± 16.4 | 22.9 ± 20.0 | 28.1 ± 30.6 | 10.4 ± 8.5 |
Median | 11 | 23 | 16 | 10 | 9 |
Range | 1–83 | 2–54 | 3–58 | 3–83 | 1–31 |
Duration of infusion (h) | |||||
Mean ± SD | 2.0 ± 0.2 | 2.1 ± 0.2 | 2.0 ± 0.1 | 2.0 ± 0.1 | 2.0 ± 0.2 |
Median | 2.0 | 2.0 | 2.0 | 2.0 | 2.0 |
Range | 1.0–2.6 | 1.9–2.6 | 1.8–2.1 | 2.0–2.3 | 1.0–2.3 |
Discontinuation of L-AMB due to adverse event [n (%)] | 9 (20) | 3 (37) | 1 (10) | 1 (14) | 4 (21) |