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. 2022 Apr 26;10:824075. doi: 10.3389/fcell.2022.824075

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Copyright © 2022 Abudula, Fan, Zhang, Li, Zhou and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Exosome^MSN increased the expression of MMP9, VEGFR2 and p-VEGFR2 in vivo. (A) MMP9 expressed in ectopic implant tissues detected by IHC. (B) VEGFR2 expressed in ectopic implant tissues detected by IHC. (C) Immunofluorescence of p-VEGFR2 in ectopic foci. The result was consistent with VEGFR2. MSNi: MSN siRNA transfection; Microscopic magnification: ×200. **, p < 0.001; *, p < 0.05; NS, no significance.