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. 2018 Sep 18;8(57):32423–32433. doi: 10.1039/c8ra05940c

Conversion of fructose to 5-HMF with different solventsa.

Entry Solvent Experimental parameter
Conversion/% Yield/% Selectivity/%
1 DMSO 100 96.7 96.7
2 DMA 87.1 31.3 35.9
3 DMF 91.8 33.5 36.5
4 NMP 96.7 70.3 72.8
5 Acetone 89.5 33.9 37.8
6 MIBK 91.5 1.3 1.5
7 sec-Butanol 92.8 26.3 28.3
8 n-Butanol 22.4 0.9 4.1
9 [EMIM]Br 50.6 5.3 10.5
10 H2O 59.9 7.8 13.0
11 DMSO/H2O (4 : 1) 82.9 5.9 7.2
a

Conditions: 56 mM fructose, 50 mg NbPW-06, 80 °C, 3 h.