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. 2022 Apr 26;13:844624. doi: 10.3389/fgene.2022.844624

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Copyright © 2022 Li, Liu, Zhang, Gu and Zhao.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Subclusters and survival analysis based on the expression level of DEGs. (A) Classification of consensus clusters. The cumulative distribution function (CDF) was set from k = 2 to 9. (B) Consensus matrix of three subclusters (k = 3). (C) Three-dimensional PCA of three subclusters according to HCC patients. (D) Kaplan–Meier (K–M) analysis of overall survival (OS) for HCC patients in TCGA cohort with different HCC clusters. (E) K–M curves of OS for HCC patients in TCGA cohort with A and C clusters. (F) Kaplan–Meier curves of OS for HCC patients in TCGA cohort with A and B clusters. (G) K–M curves of OS for HCC patients in TCGA cohort with B and C clusters. (H) K–M curves of OS for HCC patients in TCGA cohort with A + B and C clusters. (I) KM curves of OS for HCC patients in TCGA cohort with A and B + C clusters.