TABLE 2.
MICs and MBCs of gemifloxacin and ofloxacin for an E. coli test strain (ATCC 25922) and nine uropathogens cultured from the urine of patients with complicated UTIs
| Test strain | Laboratory strain no. | Inoculum (105 CFU/ml) | MIC/MBC (mg/liter)
|
|
|---|---|---|---|---|
| Gemifloxacin | Ofloxacin | |||
| E. coli | ATCC 25922 | 1.3 | 0.016/0.016 | 0.06/0.06 |
| K. pneumoniae | 595 | 3.7 | 0.03/0.03 | 0.06/0.06 |
| P. mirabilis | 414 | 2.5 | 0.125/0.250 | 0.125/0.125 |
| E. coli | 523 | 3.4 | 0.06/0.06 | 0.5/0.05 |
| P. aeruginosa | 568 | 5.6 | 1/2 | 4/4 |
| S. aureus | 83 | 7.1 | 0.008/0.008 | 0.25/0.25 |
| E. faecalis | 60 | 7.0 | 0.06/0.06 | 2/2 |
| S. aureus | 161 | 9.4 | 0.25/0.25 | 4/4 |
| S. aureus | 636 | 5.6 | 2/2 | 32/32 |
| E. faecalis | 55 | 6.0 | 0.5/2 | 32/128 |