TABLE 5.
Median (range) MUBCs
| Organism (strain) | No. of volunteers for gemifloxacin (n)a | MUBCb for gemifloxacin (μg/ml) | No. of volunteers for ofloxacin (n) | MUBCb for ofloxacin (μg/ml) |
|---|---|---|---|---|
| E. coli (ATCC 25922) | 16 (16) | 0.09 (0.03–1.84) | 16 (16) | 0.27 (0.02–2.51) |
| K. pneumoniae (595) | 16 (32) | 0.42 (0.06–7.27) | 16 (16) | 0.42 (0.08–6.62) |
| P. mirabilis (414) | 16 (48) | 0.63 (0.04–11.0) | 16 (32) | 0.51 (0.17–5.69) |
| E. coli (523) | 16 (32) | 1.02 (0.19–10.4) | 16 (32) | 2.27 (0.26–20.4) |
| P. aeruginosa (568) | 16 (16) | 18.2 (5.29–83.1) | 16 (32) | 15.0 (5.78–109.2) |
| S. aureus (83) | 16 (48) | 0.14 (0.02–1.15) | 16 (16) | 0.27 (0.20–2.51) |
| E. faecalis (60) | 16 (48) | 1.10 (0.01–11.1) | 16 (48) | 11.7 (4.09–38.6) |
| S. aureus (161) | 13 (26) | 3.34 (0.16–20.8) | 13 (13) | 17.0 (2.64–54.6) |
| E. faecalis (55) | 13 (26) | 14.1 (3.70–83.1) |
a
Values in parentheses are numbers of datum points. b For calculation of the MUBC, only pairs of data with urinary concentration and UBT (different from 0 or ≥1,024) were used if available for all volunteers of the group.