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. 2022 Apr 26;10:879877. doi: 10.3389/fcell.2022.879877

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Copyright © 2022 Liu, Qin, Liu, Mi, Zhang, Wang, Zhuang, Xu, Chen, Guo and Wu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Profiling and identification of upregulated miRNAs in Hypo-exos and in Norm-exos. (A) Heat map showing the profiles of upregulated miRNAs in Hypo-exos compared with Norm-exos. (B) Volcano map revealing nine significantly upregulated miRNAs with a ≥2 fold difference between Hypo-exos and Norm-exos. (C) The nine significantly upregulated miRNAs (≥2 fold, p < 0.05) are listed. (D) Comparison of let-7f-5p, miR-100, miR-221-5p, miR-31-5p, miR-411-3p, miR-210-3p, miR-155-5p, miR-193b-5p and miR-125a between Norm-exos and Hypo-exos by qRT-PCR. *p < 0.05, **p < 0.01.