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. 2022 Apr 26;13:873764. doi: 10.3389/fgene.2022.873764

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Copyright © 2022 Zhang, Zheng, Lv, Shi and Shi.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Correlation of the m6A risk score with different immune cell infiltration. (A) Compared with the low expression group, the immune-related scores and stromal-related scores of patients in the high-risk group were significantly increased (p < 0.001); (B) The overall immune infiltration level of glioma patients was analyzed based on the ssGSEA algorithm; (C) Correlation analysis shows that there are significant differences in the expression of multiple immune subtypes in patients in the high and low m6A groups; (D) There are differences in the expression of multiple HLA family genes between the high and low m6A groups; (E) There are also differences in the expression levels of immune therapy-related target genes between the high and low m6A groups.