Table 4.
Predictive values of coagulation parameters for surgical NEC
| Variables | The best cut-off level |
Youden index (largest) |
Sensitivity (%) |
Specifificity (%) |
PPV (%) |
NPV (%) |
|---|---|---|---|---|---|---|
| PT (s) | 16.7 | 0.49 | 65.22 | 83.82 | 73.17 | 78.08 |
| PT-INR | 1.23 | 0.29 | 34.78 | 94.20 | 80.00 | 68.09 |
| APTT (s) | 41.3 | 0.54 | 67.39 | 86.76 | 77.50 | 79.73 |
| Fib (g/L) | 1.09 | 0.35 | 50.00 | 85.29 | 65.52 | 68.24 |
| PLT (× 109/L) | 252 | 0.47 | 67.39 | 79.41 | 69.77 | 77.46 |
NEC Necrotizing Enterocolitis, PPV Positive Predictive Value, NPV Negative Predictive Value, PPV and NPV were calculated for the best cut-off levels. PT Prothrombin Time, PT-INR PT International Normalized Ratio, APTT Activated Partial Thromboplastin Time, Fib Fibrinogen, PLT Platelet Count