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. 2022 Apr 26;13:849189. doi: 10.3389/fphar.2022.849189

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Copyright © 2022 Zhang, Zeng, Peng, Tan and Wan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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| One-way sensitivity analysis results of the FOLFOX-HAIC strategy versus TACE strategy in all patients with large unresectable hepatocellular carcinoma. The tornado diagram shows the impact of varying model parameters on the incremental cost-effectiveness ratio of the FOLFOX-HAIC strategy compared to the TACE strategy. The dotted line intersecting the blue and yellow bar represents the ICER of $30,552/QALY from the base case results. OS, overall survival; PFS, progression-free survival; HR, hazard ratio; TACE, transarterial chemoembolization; FOLFOX-HAIC, hepatic arterial infusion chemotherapy with infusional fluorouracil, leucovorin, and oxaliplatin; PFD, progression-free disease; PD, progressed disease; BSC, best supportive care.