FIGURE 1.

Reported apo and compound structures of SARS-CoV-2 PLpro. Shown are unliganded and compound bound structures publicly released in the Protein Data Bank (PDB) since the beginning of the COVID-19 pandemic. The unit cell for each space group is shown (thin red lines) and the corresponding symmetry mates from the asymmetric unit are depicted with matching colours. The structures are grouped according to their bound ligands, the ligand is labelled above each unit cell, and the corresponding PDB accession numbers shown below. The obtained resolution or resolution range for each crystallographic setting is indicated.