TABLE 2.

Currently reported potencies (IC₅₀, µM) of GRL-0617 against SARS-CoV-2 PLpro.

IC50 (µM)	Primary assay	References
1.15	Ub-Rh110	Calleja et al. this issue
0.74	Ub-AMC	Shin et al. (2020)
1.50	ISG15-AMC
0.88	Ub-AMC	Ma et al. (2021)
1.68	ISG15-AMC
1.39	Z-RLRGG-AMC	Zhao et al. (2021)
1.61	Z-RLRGG-AMC	Shen et al. (2021)
2.1	Z-RLRGG-AMC	Fu et al. (2021)
2.2	(Dabcyl)-FTLRGGAPTKV-(Edans)	Gao et al. (2020)
2.3	LKGG-(CV-2)	Osipiuk et al. (2021)
2.4	Z-RLRGG-AMC	Freitas et al. (2020)