TABLE 3.
Review ID | Reference ID | IC50 (µM) | Primary assay | References | Review ID | Reference ID | IC50 (µM) | Primary assay | References |
---|---|---|---|---|---|---|---|---|---|
1 | Snyder_495 (2) | 5.1 | LKGG-(CV-2) | Osipiuk et al. (2021) | 20 | XR8-89 (94) | 0.11 | Z-RLRGG-AMC | Shen et al. (2021) |
2 | Snyder_530 (3) | 6.4 | 21 | XR8-69 (89) | 0.37 | ||||
3 a | Snyder_496 | — | 22 | XR8-23 (72) | 0.39 | ||||
4 a | Snyder_494 | — | 23 | XR8-32-1 (75) | 0.97 | ||||
5 | 5 | 17 | 24 | XR8-30 (74) | 0.75 | ||||
6 | 6 | 7 | 25 | DY-3-63 (18) | >100 | ||||
7 | 7 | 13 | 26 | ZN-2-193 (21) | >10 | ||||
8 | ZN-2-184 (5) | 1.01 | Z-RLRGG-AMC | Shen et al. (2021) | 27 | ZN-2-192 (20) | 4.8 | ||
9 | ZN-2-186 (7) | 1.2 | 28 | Jun9-13-7 | 7.3 | (Dabcyl)-FTLRGGAPTKV-(Edans) | Ma et al. (2021) | ||
10 | DY2-144 (14) | 1.3 | 29 | Jun9-13-9 | 6.7 | ||||
11 | ZN-2-188–2 (11) | 4.3 | 30 | Jun9-53-2 | 0.89 | ||||
12 | ZN-3-56 (13) | 3.9 | 31 | Jun9-72-2 | 0.67 | ||||
13 | ZN-3-80 (65) | 0.59 | 32 | Jun9-87-3 | 0.80 | ||||
14 | XR8-8 (66) | 1.3 | 33 | Jun9-87-2 | 0.90 | ||||
15 | ZN-3-79 (59) | 1.9 | 34 | Jun9-87-1 | 0.87 | ||||
16 | DY-2-153 (60) | 1.8 | 35 | Jun9-75-5 | 0.56 | ||||
17 | XR8-24 (73) | 0.56 | 36 | Jun9-84-3 | 0.67 | ||||
18 | XR8-65 (86) | 0.33 | 37 | Jun9-75-4 | 0.62 | ||||
19 | XR8-83 (92) | 0.21 | 38 | Jun9-85-1 | 0.66 |
3 and 4 structures were published in the PDB, prior to publication of (Osipiuk et al., 2021), but excluded from the final publication. The two compounds were presented in this Review to illustrate their structural features.