Table 2.

Quality assessment of the included studies.

References	Selection	Ascertainment		Causality				Reporting
	Does the patients represent the whole experience of the centers	Was the exposure adequately ascertained	Was the outcome adequately ascertained	Were other alternative causes that may explain the observation ruled out*	Was there a challenge/rechallenge phenomenon*	Was there a dose–response effect*	Was follow-up long enough for outcomes to occur	Were the cases described with sufficient to allow other investigators to replicate
Septal myectomy
Mazine et al. (12)	YES	YES	NO	YES	YES	N	YES	YES
Xu et al. (26)	YES	YES	YES	YES	NO	N	YES	YES
Yao et al. (13)	YES	YES	YES	YES	N	N	YES	YES
Lai et al. (14)	YES	YES	YES	YES	N	N	YES	YES
Rastegar et al. (15)	YES	YES	NO	YES	NO	N	YES	YES
Vanderlaan et al. (16)	YES	YES	NO	YES	N	N	NO	YES
An et al. (17)	YES	YES	NO	YES	N	N	YES	YES
Cavigli et al. (18)	YES	YES	YES	YES	YES	N	YES	YES
Laredo et al. (27)	YES	YES	NO	YES	YES	N	YES	YES
Schleihauf et al. (28)	YES	YES	NO	YES	N	N	YES	YES
Vrancic et al. (19)	YES	YES	NO	YES	N	N	YES	YES
Nguyen et al. (20)	NO	YES	NO	YES	N	N	YES	YES
Afanasyev et al. (21)	YES	YES	YES	YES	N	N	YES	YES
Antal et al. (22)	YES	YES	NO	YES	YES	N	YES	YES
Islam et al. (23)	YES	YES	YES	YES	NO	N	N	YES
Lapenna et al. (24)	NO	YES	NO	YES	N	N	YES	YES
Zhu et al. (29)	YES	YES	NO	YES	YES	N	YES	YES
Sun et al. (25)	NO	YES	NO	YES	YES	N	YES	YES
Endocardial radiofrequency ablation
Lawrenz et al. (30)	YES	YES	YES	YES	NO	N	YES	YES
Sreeram et al. (36)	YES	YES	NO	NO	YES	N	YES	YES
Cooper et al. (31)	N	YES	YES	YES	N	N	YES	YES
Crossen et al. (32)	N	YES	YES	YES	YES	N	YES	YES
Shelke et al. (33)	YES	YES	NO	YES	YES	N	YES	YES
Beaser et al. (34)	N	YES	NO	YES	N	N	NO	YES
Zuo et al. (35)	YES	YES	NO	YES	N	N	YES	YES

^*Mostly relevant to cases of adverse drug events.

N, not documented.