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. 2022 Apr 26;9:807436. doi: 10.3389/fcvm.2022.807436

TABLE 5.

Significant sleep apnea-specific heart rate variability parameters associated with AMI risk.

HRV variables* Unadjusted
Model 1
Model 2
OR (95% CI) p-Value OR (95% CI) p-Value OR (95% CI) p-Value
minSpO2-related
LF > 77.2 0.69 (0.49−0.96) 0.028 0.62 (0.45−0.88) 0.007 0.64 (0.45−0.90) 0.011
NN > 1.02 0.50 (0.36−0.70) <0.001 0.48 (0.34−0.67) <0.001 0.49 (0.34−0.69) <0.001
RE-related
TP > 1570 0.62 (0.45−0.87) 0.006 0.57 (0.41−0.80) 0.002 0.61 (0.43−0.86) 0.005
NN > 1.02 0.49 (0.35−0.68) <0.001 0.46 (0.33−0.64) <0.001 0.49 (0.35−0.68) <0.001
SDNN > 0.101 0.68 (0.49−0.96) 0.029 0.64 (0.45−0.90) 0.012 0.69 (0.48−0.98) 0.041
NRE-related
LF/HF > 0.91 1.63 (1.17−2.27) 0.004 1.34 (0.95−1.88) 0.098 1.36 (0.96−1.92) 0.084

*The fourth quartiles were shown with the first quartile as the referenced group. Model 1 adjusted for age, gender, and BMI. Model 2 adjusted for age, gender, BMI, hypertension, dyslipidemia, eGFR, and diabetes mellitus.

OR, odds ratio; minSpO2, minimal oxygen saturation; RE, respiratory event; NRE, non-respiratory events; TP, total power; SDNN, standard deviation of NN interval; LF, low-frequency; HRV, heart rate variability.