Table 1.
Selected epitopes for designing the vaccine along with their antigenicity, allergenicity, conservancy and IFN-γ inducing potential
| Protein | Epitope sequence | HLA-I (Netmhc4- IEDB) | HLA-II (RANKPEP/ IEDB) | Linear B Cell (BEPIPRED/ IEDB) | Antigenicity | IFN-γ stimulation | Allergenicity | Conservancy |
|---|---|---|---|---|---|---|---|---|
| RV2346 | QTDSAVGSSW | + | + | _ | 1.4000 | 1 | Non-applicable | 96% |
| DVLAAGDFWGGAGSVACQE | + | + | + | 0.4957 | 1 | Non-Allergen | 58% | |
| RV2347 | HAMRDMAGR | + | + | - | 0.7163 | -0.14355781 | Non-applicable | 96% |
| ARRMWASAQNISGAG | + | + | + | 0.6245 | 1 | Non-Allergen | 84% | |
| RV3614 | WTADPIIGV | + | + | + | 0.5996 | 0.35940912 | Non-applicable | 80% |
| RIDHVELSARVAWMSES | + | + | + | 0.6176 | 1 | Non-Allergen | 90% | |
| RV3615 | HTAGVDLAK | + | + | - | 1.2063 | 0.11063872 | Non-applicable | 60% |
| SSLHTAGVDLAKSLRIA | + | + | - | 0.7673 | 0.049221663 | Non-Allergen | 58% | |
| RV2031 | HPRSLFPEF | + | + | + | 0.5001 | 0.16584561 | Non-applicable | 64% |
| ELFAAFPSFAGLRPT | + | + | + | 0.5372 | 0.65327194 | Non-Allergen | 64% |