Table 2. Distribution of CYP2C19 Alleles, Genotype and Phenotype (PTRG-Genotype Cohort: n=8163).
| Allele | Frequency no. (%) | Genotype | Frequency no. (%) | Phenotype | Frequency no. (%) |
|---|---|---|---|---|---|
| *1 | 9950 (60.9) | *1/*1 | 3011 (36.9) | Extensive metabolizer | 3098 (38.0) |
| *2 | 4486 (27.5) | *1/*2 | 2786 (34.1) | Intermediate metabolizer | 3906 (47.9) |
| *3 | 1738 (10.6) | *1/*3 | 1055 (12.9) | Poor metabolizer | 1159 (14.2) |
| *17 | 152 (0.9) | *1/*17 | 87 (1.1) | ||
| *2/*2 | 606 (7.4) | ||||
| *2/*3 | 440 (5.4) | ||||
| *2/*17 | 48 (0.6) | ||||
| *3/*3 | 113 (1.4) | ||||
| *3/*17 | 17 (0.2) | ||||
| *17/*17 | 0 (0) |
CYP, cytochrome P450.