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. Author manuscript; available in PMC: 2022 May 10.
Published in final edited form as: Am J Pharmacogenomics. 2003;3(3):157–172. doi: 10.2165/00129785-200303030-00002

Table IV.

Polymorphisms in the GSTM1 gene and associated cancer risks[49,50,5254]

Allele Frequency in Caucasian populations Frequency in colorectal cancer patients Cancer risks
M1*A 0.2 0.19 Decreased risk of bladder and breast cancer
M1*B 0.2 0.14 Decreased risk of pituitary adenomas
M1*O 0.59 0.65 Increased risk of lung, colon, bladder, and post-menopausal breast cancer