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. Author manuscript; available in PMC: 2022 May 10.
Published in final edited form as: Am J Pharmacogenomics. 2003;3(3):157–172. doi: 10.2165/00129785-200303030-00002

Table V.

Polymorphisms in the GSTP1 gene and associated cancer risks[52,8385,87,9296]

Allele Frequency in Caucasian populations Cancer risks
P1*A 0.65 Cisplatin resistance
P1*B 0.262 Favorable response to cisplatin. Increased susceptibility to lung, bladder and testicular tumors
P1*C 0.068 Predominant genotype in malignant glioma. Protective for breast cancer